Polysiloxane based on hydroxyl-containing monomer. Preparation, properties and biomedical application

• DOI: 10.1007/s11172-019-2522-3
• Publication Date: 2019-06-11T08:02:46Z
• Authors: T. S. Lyubova; N. S. Zakharycheva; E. A. Zakharychev; S. A. Lermontova; E. Yu. Ladilina; L. G. Klapshina
• Keywords: Siloxane; Aqueous medium

A method for synthesis of hyperbranched polysiloxane based on N-methyl-N-(2,3,4,5,6-pentahydroxyhexyl)-N’-(3-triethoxysilylpropyl)urea is proposed. In water, the polymer forms nanoparticles capable of holding low soluble luminophores (tetracyanotetraarylporphyrazines) due to non-covalent interaction. Intensively luminescent stable aqueous suspensions based on non-toxic siloxane nanoparticles can be used in bioimaging.