Occurrence of pulmonary embolism related to COVID-19

• DOI: 10.1007/s11239-020-02292-4
• Publication Date: 2020-10-07T00:03:03Z
• Authors: Marie Hauguel-Moreau; Mostafa El Hajjam; Quentin De Baynast; Antoine Vieillard...; Anne-Sophie Lot; Thierry Chinet; Hazrije Mustafic; Céline Bégué; Robert Yves Carlier; Guillaume Geri; Olivier Dubourg; Sébastien Beaune; Nicolas Mansencal
• Keywords: Hematology; 2019-20 coronavirus outbreak

Recent reports have suggested an increased risk of pulmonary embolism (PE) related to COVID-19. The aim this cohort study is compare the incidence PE during a 3-year period and assess characteristics in We studied consecutive patients presenting with (January 2017-April 2020). Clinical presentation, computed tomography (CT) biological markers were systematically assessed. recorded global number hospitalizations COVID-19 pandemic same 2018-2019. included 347 patients: 326 without 21 Patients experienced more likely dyspnea (p=0.04), had lower arterial oxygen saturation (p<0.001), higher C-reactive protein white blood cell (WBC) count (p<0.0001 p=0.001, respectively), significantly in-hospital mortality (14% versus 3.4%, p=0.04). Among patients, diagnosis was performed at admission 38% (n=8). hospitalization (n=13) (p=0.01), less proximal (p=0.02), heart rate (p=0.009), CT severity score (p=0.001), (p=0.006) WBC (p=0.04). During outbreak, 97.4% increase observed as compared 2017-2019 proportion 3.7% 1.3% 2018-2019 (p<0.0001). In conclusion, leads dramatic PE. Physicians should be aware that may diagnosed admission, but also after several days hospitalization, different clinical, features thrombotic disease.