Synthesis, characterization and antimicrobial properties of lipophilic palladium complexes bearing iminopyridine ligands

• DOI: 10.1007/s11243-015-9977-3
• Publication Date: 2015-09-10T22:13:45Z
• Authors: Patrick T. Gormley; B. Ninh Khuong; Courtney M. Dickie; Ashley M. Taweel; Heather L. Blundon; Josée-Marie E. J....; Adam F. LeBlanc; Tara S. Murphy; Curran G. Tompkins; Christopher M. Vo...; Andreas Decken; Felix J. Baerlocher; Tyson J. MacCormack; Stephen A. Westcott
• Keywords: 01 natural sciences; 0104 chemical sciences; 3. Good health

The reaction of [PdCl2(η2-coe)]2 (coe = cis-cyclooctene) with nine lipophilic iminopyridine ligands (NN′, 1a–i) afforded the corresponding metal complexes cis-[PdCl2(NN′)] (2a–i) with concomitant loss of the labile coe ligands. All iminopyridine complexes were characterized by physicochemical and spectroscopic methods. The molecular structures of two complexes, 2a and 2b, were determined by single crystal X-ray diffraction studies. All complexes were tested for their potential antifungal and antibacterial activities.