Phytochemical composition of Potentilla anserina L. analyzed by an integrative GC-MS and LC-MS metabolomics platform

• DOI: 10.1007/s11306-012-0473-x
• Publication Date: 2012-11-16T21:59:12Z
• Authors: Angela Mari; David Lyon; Lena Fragner; Paola Montoro; Sonia Piacente; Stefanie Wienkoop; Volker Egelhofer; Wolfram Weckwerth
• Keywords: Phytochemical; Chlorogenic Acid

Potentilla anserina L. (Rosaceae) is known for its beneficial effects of prevention pre-menstrual syndrome (PMS). For this reason P. processed into many food supplements and pharmaceutical preparations. Here we analyzed hydroalcoholic reference extracts compared them with various different pharmacies using an integrative metabolomics platform comprising GC-MS LC-MS analysis software toolboxes data alignment (MetMAX Beta 1.0) multivariate statistical (COVAIN 1.0). Multivariate statistics the integrated showed strong differences between plant extract formulations. Different groups compounds such as chlorogenic acid, kaempferol 3-O-rutinoside, acacetin 7-O-rutinoside, genistein were reported first time in species. The typical fragmentation pathway isoflavone confirmed identification active compound that was present abundances all analyzed. As a result have revealed extraction procedures from vendors produce chemical compositions, e.g. concentrations. Consequently, treatment may effects. provides highest resolution phytochemical composition mean to define subtle