Impact of DWI and ADC values in Ovarian-Adnexal Reporting and Data System (O-RADS) MRI score

diffusion-weighted imaging (DWI); magnetic resonance imaging; O-RADS; ovarian carcinoma Diffusion Magnetic Resonance Imaging ROC Curve Humans Reproducibility of Results Female Sensitivity and Specificity Magnetic Resonance Imaging Retrospective Studies
DOI: 10.1007/s11547-023-01628-3 Publication Date: 2023-04-25T11:15:01Z
ABSTRACT
Abstract Purpose Introduce DWI and quantitative ADC evaluation in O-RADS MRI system observe how diagnostic performance changes. Assess its validity reproducibility between readers with different experience female pelvic imaging. Finally, evaluate any correlation value histotype malignant lesions. Materials Methods In total, 173 patients 213 indeterminate adnexal masses (AMs) on ultrasound were subjected to examination, from which 140 172 AMs included the final analysis. Standardised sequences used, including DCE sequences. Two readers, blinded histopathological data, retrospectively classified according scoring system. A analysis method was applied by placing a ROI maps obtained single-exponential considered benign (O-RADS score 2) excluded Results Excellent inter-reader agreement found classification of lesions ( K = 0.936; 95% CI). ROC curves created determine optimal cut-off for variable categories 3–4 4–5, respectively, 1.411 × 10 –3 mm 2 /sec 0.849 /sec. Based these values, 3/45 22/62 upgraded, 4 5, while 4/62 downgraded 3. values correlated significantly ovarian carcinoma p < 0.001). Conclusion Our study demonstrates prognostic potential better radiological standardisation characterisation AMs.
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