Post-Discharge Health Status and Symptoms in Patients with Severe COVID-19

• DOI: 10.1007/s11606-020-06338-4
• Publication Date: 2021-01-14T15:23:43Z
• Authors: Himali Weerahandi; Katherine A. Hochman; Emma Simon; Caroline Blaum; Joshua Chodosh; Emily Duan; Kira Garry; Tamara Kahan; Savannah L. Karme...; Hannah C. Karpel; Felicia Mendoza; Alexander M. Prete; Lindsey Quintana; Jennifer Rutishauser; Leticia Santos Ma...; Kanan Shah; Sneha Sharma; Elias Simon; Ana Z. Stirniman; Leora I. Horwitz
• Keywords: Interquartile range

Little is known about long-term recovery from severe COVID-19 disease. Here, we characterize overall health, physical and mental health of patients 1 month after discharge for COVID-19. This was a prospective single system observational cohort study ≥ 18 years hospitalized with laboratory-confirmed disease who required at least 6 l oxygen during admission, had intact baseline cognitive functional status, were discharged alive. Participants enrolled between 30 40 days discharge. Outcomes elicited through validated survey instruments: the PROMIS® Dyspnea Characteristics Global Health-10. A total 161 (40.6% eligible) enrolled; 152 (38.3%) completed survey. Median age 62 (interquartile range [IQR], 50–67); 57 (37%) female. Overall, 113/152 (74%) participants reported shortness breath within prior week (median score 3 out 10 [IQR 0–5]), vs 47/152 (31%) pre-COVID-19 infection (0, IQR 0–1), p < 0.001. also rated their as worse in post-COVID state (43.8, standard deviation 9.3; 47.3, SD 9.3) compared to pre-COVID state, (54.3, 54.3, 7.8, respectively), both Physical means general US population are 50 (SD 10). 52/148 (35.1%) without requirements needed home hospital discharge; 20/148 (13.5%) still using time Patients typically experience sequelae affecting respiratory several weeks