Preparation and application of highly porous aerogel-based bioactive materials in dentistry

• DOI: 10.1007/s11706-014-0231-2
• Publication Date: 2014-03-18T03:46:06Z
• Authors: Andrea Kuttor; Melinda Szalóki; Tünde Rente; Farkas Kerényi; József Bakó; István Fábián; István Lázár; Attila Jenei; Csaba Hegedüs
• Keywords: Anyagtudományok és technológiák; 0301 basic medicine; 03 medical and health sciences; Műszaki tudományok

In this study, the possibility of preparation and application of highly porous silica aerogel-based bioactive materials are presented. The aerogel was combined with hydroxyapatite and β-tricalcium phosphate as bioactive and osteoinductive agents. The porosity of aerogels was in the mesoporous region with a maximum pore diameter of 7.4 and 12.7 nm for the composite materials. The newly developed bioactive materials were characterized by scanning electron microscopy. The in vitro biological effect of these modified surfaces was also tested on SAOS-2 osteogenic sarcoma cells by confocal laser scanning microscopy.