Definition of Periprosthetic Joint Infection: Is There a Consensus?

• DOI: 10.1007/s11999-011-1971-2
• Publication Date: 2011-07-12T15:01:58Z
• Authors: Javad Parvizi; Christina Jacovides; Benjamin Zmistowski; Kwang Am Jung
• Keywords: Gold standard (test)

The diagnosis of periprosthetic joint infection (PJI) continues to pose a challenge. While many diagnostic criteria have been proposed, gold standard for is lacking. Use multiple within the arthroplasty community raises concerns in patient treatment and comparison research pertaining PJI.We (1) determined variation existing criteria, (2) compared proposed new set that incorporates aspirate cell count analysis, (3) investigated variations between criteria.We retrospectively identified 182 patients undergoing 192 revision knee arthroplasties who had preoperative aspiration analysis at our institution April 2002 November 2009. We excluded 20 cases due insufficient laboratory parameters, leaving 172 analysis. applied six previously published sets PJI determine its incidence using each criteria. then these where disagreement occurred.We 41 (24%) which least one established classified case as infected while other uninfected. With infected/uninfected ratio was 92/80. large variance sensitivity (54%-100%), specificity (39%-100%), accuracy (53%-100%) when reference standard.The discrepancy definitions complicates interpretation literature failed TKAs owing PJI. Based on findings, we suggest establishing common utilizing improve facilitate literature.Level III, study. See Guidelines Authors complete description levels evidence.