Fractures in Geriatric Mice Show Decreased Callus Expansion and Bone Volume

• DOI: 10.1007/s11999-014-3829-x
• Publication Date: 2014-08-08T17:36:15Z
• Authors: Luke A. Lopas; Nicole S. Belkin; Patricia L. Mutyaba; Chancellor F. Gray; Kurt D. Hankenson; Jaimo Ahn
• Keywords: Osteoid; Callus; Bone fracture

Poor fracture healing in geriatric populations is a significant source of morbidity, mortality, and cost to individuals society; however, fundamental biologic understanding age-dependent remains elusive. The development an aged-based model system would allow for mechanistic that could guide future treatments.