Improving Nonenzymatic Biosensing Performance of Electrospun Carbon Nanofibers decorated with Ni/Co Particles via Oxidation

• DOI: 10.1007/s12010-022-03833-8
• Publication Date: 2022-02-16T05:02:30Z
• Authors: Ali Mohammadpour-...; Saeedeh Mazinani; Farhad Sharif; Ali Mohammad Baza...
• Keywords: Nanofibers; Reproducibility of Results; Biosensing Techniques; Electrochemical Techniques; 02 engineering and technology; 01 natural sciences; Carbon; 0104 chemical sciences; Glucose; Humans; 0210 nano-technology; Electrodes

Abstract Electrochemical nonenzymatic biosensors with no immobilization and degradation problem, have recently attracted growing attention due to stability and reproducibility. Here, a comparative study was conducted to precisely evaluate the nonenzymatic glucose sensing of pure/oxidized Ni, Co, and their bimetal nanostructures grown on electrospun carbon nanofibers (ECNFs). This method provides a low-cost free stand electrode. The prepared nanostructures with superb physiochemical features exhibited sensitivity (from 66.28 to 610.6 μA mM−1 cm−2), linear range of 2-10 mM, limit of detection in the range of 1 mM, and response time (<5 s), besides outstanding selectivity and applicability for glucose detection in the human serum. Regarding Co-C and Ni-C phase diagrams, solid-state diffusion phenomena, and rearrangement of dissolved C atoms after migration from metal particles was discussed. This study undoubtedly provides new prospects on nonenzymatic biosensing performance of mono-metal, bimetal, and oxide compounds of Ni and Co elements, which is useful for the fabrication of biomolecules detecting devices.