CSF Volumetric Analysis for Quantification of Cerebral Edema After Hemispheric Infarction

• DOI: 10.1007/s12028-015-0204-z
• Publication Date: 2015-10-05T19:37:22Z
• Authors: Rajat Dhar; Kristy Yuan; Tobias Kulik; Yasheng Chen; Laura Heitsch; Hongyu An; Andria Ford; Jin-Moo Lee
• Keywords: Midline shift; Cerebral edema; Cistern; Stroke

Malignant cerebral edema (CED) complicates at least 20 % of large hemispheric infarcts (LHI) and may result in neurological deterioration or death. Midline shift (MLS) is a standard but crude measure of edema severity. We propose that volumetric analysis of shifts in cerebrospinal fluid (CSF) over time provides a reliable means of quantifying the spectrum of edema severity after LHI.