Case Report: Inflammatory Myofibroblastic Tumor of the Duodenum

• DOI: 10.1007/s12029-008-9042-y
• Publication Date: 2009-01-13T11:48:59Z
• Authors: G. R. Wynn; A. Giles; A. S. Steger; M. L. Wilkinson
• Keywords: Esophagogastroduodenoscopy; Epigastric pain

We report a very rare case of inflammatory myofibroblastic tumor of the duodenum. A 16-year-old boy underwent esophagogastroduodenoscopy for intermittent epigastric pain, night sweats, and malaise.An exophytic mass lesion was found in the first part of the duodenum, but biopsies were non-diagnostic. Computed tomography confirmed a 60-mm mass with no lymphadenopathy, and the patient underwent surgical resection. Histology revealed spindle cells with the morphological and immunophenotypical profile of myofibroblasts on a background of mixed inflammatory infiltrate, typical of inflammatory myofibroblastic tumor. Six months after surgery, the patient developed a recurrence, and this was successfully treated by immunosuppression. Currently, the patient is asymptomatic, and there is no radiological or pathological evidence of disease.