Performance of a semiconductor SPECT system: comparison with a conventional Anger-type SPECT instrument

• DOI: 10.1007/s12149-012-0653-9
• Publication Date: 2012-09-05T03:28:48Z
• Authors: Yasuyuki Takahashi; Masao Miyagawa; Yoshiko Nishiyama; Hayato Ishimura; Teruhito Mochizuki
• Keywords: Cadmium zinc telluride; Spect imaging; Semiconductor detector

The performance of a new single photon emission computed tomography (SPECT) scanner with cadmium-zinc-telluride (CZT) solid-state semiconductor detector (Discovery NM 530c; D530c) was evaluated and compared to conventional Anger-type SPECT dual-detector camera (Infinia). Three different phantom studies were performed. Full width at half maximum (FWHM) measured using line sources placed locations in cylindrical phantom. Uniformity phantoms 3 diameters (80, 120, 160 mm). Spatial resolution hot-rod various (5, 9, 13, 16, 20 myocardial also performed, acquiring projection data without defects, evaluating the interference liver gallbladder radioactivity. In clinical study, D530c employed list-mode raw acquisition electrocardiogram (ECG)-gated over 10-min period. From data, 1-, 3-, 5-, 7- images reconstructed. FWHM D503c 1.73–3.48 mm (without water) 3.88–6.64 (with water), whereas Infinia 8.17–12.63 15.48–16.28 water). Non-uniformity larger for than Infinia. Truncation artifacts observed Φ160 contrast ratio, as defined by defect/non-defect better Infinia, influence from radioactivities less. Quantitative gated (QGS) software demonstrated significant differences between captured period, relative those acquired periods <5 min; there no difference ejection fractions calculated capture ≥5 min (p < 0.05). is superior regard both spatial sensitivity. this these advantages confirmed setting, QGS software.