Deep Brain Stimulation for Consciousness Disorders; Technical and Ethical Considerations

• DOI: 10.1007/s12152-024-09570-5
• Publication Date: 2024-07-30T08:02:11Z
• Authors: Alceste Deli; Alexander L. Green
• Keywords: Persistent vegetative state; Dignity; Neuromodulation; Transcranial Direct Current Stimulation

Abstract Disorders of Consciousness (DoC) result in profound functional impairment, adversely affecting the lives a predominantly younger patient population. Currently, effective treatment options for those who have reached chronicity (prolonged symptom duration over 4 weeks) are extremely limited, with majority such cases facing life-long dependence on carers and poor quality life. Here we briefly review current evidence caseload, diagnostic management United Kingdom (UK), States America (USA) European Union (EU). We identify key differences as well similarities these approaches across respective healthcare systems, highlighting unmet needs this subsequently present past efforts most recent advances field surgical modulation consciousness through implantable neurostimulation systems. examine ethical dilemmas that approach may pose, proposing mediating solutions methodological adjustments to address concerns. Overall, argue there is strong case utilisation deep brain stimulation (DBS) DoC cohort. This based both promising results clinical trials technological developments. propose revitalization neuromodulation multicenter, multidisciplinary strict monitoring guidelines, order not only advance but also ensure safeguarding patients’ welfare dignity.