Pathologies digestives hautes associées aux anti-inflammatoires non stéroïdiens

• DOI: 10.1007/s12157-016-0665-5
• Publication Date: 2016-05-25T12:47:54Z
• Authors: R. Sombié; D. Zongo-Napon; A. Guingané; A. Tiendrébéogo; A. Bougouma
• Keywords: 03 medical and health sciences; 0302 clinical medicine

assess the pathology of upper digestive tract associated with NSAIDs. it is a prospective study from June 2012 to July 2014 including, patients under treatment nonsteroidal anti-inflammatory drug. They were seen in consultation for gastrointestinal symptoms (abdominal pain, dyspepsia, hematemesis, melena, vomiting), and had undergone endoscopy. NSAIDs considered as cause endoscopic lesions if taken during preceding two weeks. Gastric biopsy search Helicobacter pylori was not systematic. A total 142 recruited, among them 72 men (50.7%). The average age 48.8 years. There 45 hypertension (31.7%), 11with valvular disease (7.7%). Twenty-six rheumatic disease, or 16.2%. NSAID use resulting self-medication 34% cases. Ibuprofen most antiinflammatory used (50%). frequent indication endoscopy epigastric pain (64%), followed by hematemesis / melena (29.6 %). duration more than 12 months 29 (20.4%), between one three 27 (19%) 14 days 52 (36.6%). Peptic ulcer observed 61 (42.9%). (18.3%) taking peptic (53.8%). acid acetyl salicylic low dose (<300 mg) 26 (18.3%), which presented (46.1%) bleeding (11.5%). Dyspepsia 18 (12.7%). risk male gender (OR = 1.4 95% CI: 0.7 2.7), 4.9 CI 1.3 10.9).