Is it Necessary to Perform Sentinel Lymph Node Biopsy in Thin Melanoma? A Retrospective Single Center Analysis

• DOI: 10.1007/s12253-019-00769-z
• Publication Date: 2019-12-02T21:02:39Z
• Authors: A. Kocsis; L. Karsko; Zs. Kurgyis; Zs. Besenyi; L. Pavics; E. Dosa-Racz; E. Kis; E. Baltas; H. Ocsai; E. Varga; B. Bende; A. Varga; G. Mohos; I. Korom; J. Varga; L. Kemeny; I. B. Nemeth; J. Olah
• Keywords: Breslow Thickness; Mitotic index

Abstract Sentinel lymph node biopsy (SLNB) is a standard procedure for regional staging and still has the most important prognostic value outcome of patients with thin melanoma. In addition to ulceration, SLNB had be considered even single mitotic figure in (<1 mm) melanoma according AJCC7th guideline, therefore, retrospective review was conducted involving 403 pT1 patients. Among them, 152 suffered from pT1b ulcerated or rate ≥ 1/ mm 2 melanomas system. performed 78 cases, which nine (11.5%) showed SLN positivity. From interestingly, we found relatively high positive sentinel (6/78–8%) case primary ˂0.8 mm. Moreover, presence regression increased probability positivity by 5.796 fold. After reassessing pT stage based on new AJCC8 th , 37 cases were reordered into pT1a category. There no significant relation between other characteristics examined (age, gender, Breslow, Clark level, mitosis index) Based our data, suggest that alone not sufficiently powerful predictor status melanomas. If strict histopathological definition criteria are applied, might an additional adverse feature aids identifying T1 likely SLN-positive. proved independent factor Our results propose also at regressive (˂0.8