Growth pattern can be used as a new characteristic to predict malignancy in breast cancer

• DOI: 10.1007/s12282-019-01041-7
• Publication Date: 2020-02-06T14:03:22Z
• Authors: Bin Wang; Lizhe Zhu; Chenyang He; Minghui Tai; Can Zhou; Guanqun Ge; Huimin Zhang; Jianjun He; Ke Wang
• Keywords: Surgical oncology

To date, anatomic tumor length is a key criterion for cancer staging and can be used to evaluate the effectiveness of therapies. This article describes growth pattern that as new characteristic represent disease burden features predict lymphatic metastasis.Patients with breast were included in this 10-year (1999-2008) hospital-based multicenter retrospective study. The pathologic length/height ratio was illustrate correlation between features, behaviors treatments malignancies. most appropriate chosen based on comprehensive evaluation p value changing trend each characteristic.The sample consisted 4211 women diagnosed cancer. Among them, 2037 patients complete length, width height information final analysis. There 2.34 ± 4.77 metastatic lymph nodes spheroid tumors 3.21 5.82 ellipsoid when cutoff point 2. In addition, proportion ellipsoidal gradually increased from 54.36 56.67% upper outer quadrant (UOQ) 6.7 9.03% central region an increase point. ER + PR significantly decreased 50.1 45.35% ER-PR 32.73 36.24% Additionally, best length/weight distinguish 2.This study described first time how correlated malignancy it influences selection therapeutic strategies patients.