Nipple–areolar complex malposition in breast reconstruction after nipple-sparing mastectomy: a multi-institutional retrospective observational study in Japan

• DOI: 10.1007/s12282-024-01578-2
• Publication Date: 2024-04-08T18:02:05Z
• Authors: Sayuri Kato; Hiroki Mori; Miho Saiga; Satoko Watanabe; Shinsuke Sasada; Ayano Sasaki; Akiko Ogiya; Mao Yamamoto; Kazutaka Narui; Junji Takano; Hirohito Seki; Naomi Nagura; Makoto Ishitobi; Tadahiko Shien
• Keywords: Adult; Mammaplasty; Mastectomy, Subcutaneous; Breast Implants; Breast Neoplasms; Middle Aged; Surgical Flaps; Postoperative Complications; Japan; Nipples; Humans; Female; Retrospective Studies; Aged

Abstract Background Position of the nipple-areolar complex (NAC) is an important factor in the aesthetic impression of the breast, and NAC malposition is often an issue in breast reconstruction after nipple-sparing mastectomy (NSM). The purpose of this study was to evaluate the degree of NAC malposition depending on several factors using data quantified with the Mamma Balance application (Medic Engineering K.K., Kyoto, Japan). Methods Patients who underwent unilateral breast reconstruction after NSM at 8 hospitals in Japan between 2007 and 2020 were retrospectively investigated. Using Mamma Balance, NAC malposition was quantified separately in horizontal and vertical directions using patient photographs from pre-operatively and 6–24 months post-operatively. The degree of malpositioning was then statistically compared using various factors. Results The NAC deviated more cranially and medially with implants than with flaps. Cases with latissimus dorsi flap showed lateral malposition more often than cases with deep inferior epigastric artery perforator flap. With flaps, lateral incisions showed more lateral malposition and peri-areolar incisions tended to show more medial NAC malposition. In cases with severe post-operative infection of the implant, the NAC tended to deviate cranially. In radiation cases, the NAC deviated cranially. No significant difference was observed according to degree of breast ptosis or use of the pull-down operation. Only a very weak correlation was observed between a larger amount of mastectomy and more cranial NAC malposition with both flaps and implants. Conclusions This study provides insights into the tendencies and characteristics of NAC malposition.