Dexamethasone Intravitreal Implant in Diabetic Macular Edema: Real-Life Data from a Prospective Study and Predictive Factors for Visual Outcome

• DOI: 10.1007/s13300-017-0332-x
• Publication Date: 2017-11-06T01:18:44Z
• Authors: Irini Chatziralli; Panagiotis Theodo...; Efstratios Parikakis; Eleni Dimitriou; Tina Xirou; George Theodossiadis; Stamatina Α. Kaba...
• Keywords: Diabetic macular edema

The purpose of the study was to evaluate long-term anatomical and functional outcomes in patients with diabetic macular edema (DME) treated intravitreal dexamethasone implant determine predictive factors for final visual outcome.The included 54 DME refractory previous antivascular endothelial growth factor (anti-VEGF) who were implant. Predictive outcome assessed. In addition, change best-corrected acuity (BCVA) percentage resolution evaluated.At end 12-month follow-up, gained + 5.2 letters (about 1 Snellen line), while 57.4% presented total edema. Negative found be increasing age, thickness, phakic status, presence intraretinal fluid, hyperreflective foci, hard exudates, as well external limiting membrane ellipsoid zone disruption. mean number injections 2.1.The various that possibly define patient prognosis after cases have been studied. long follow-up showed seems a safe effective treatment this disease, requiring limited injections.