Influence of incorrect staging of colorectal carcinoma on oncological outcome: are we playing safely?

• DOI: 10.1007/s13304-021-01095-3
• Publication Date: 2021-07-06T19:02:31Z
• Authors: Claudia Reali; Gabriele Bocca; Ian Lindsey; Oliver Jones; Chris Cunningham; Richard Guy; Bruce George; Stephen Boyce
• Keywords: 03 medical and health sciences; 0302 clinical medicine; Rectal Neoplasms; Colonic Neoplasms; Humans; Margins of Excision; Original Article; Adenocarcinoma; Neoadjuvant Therapy; Neoplasm Staging; 3. Good health

Accurate preoperative staging of colorectal cancers is critical in selecting patients for neoadjuvant therapy prior to resection. Inaccurate staging, particularly understaging, may lead involved resection margins and poor oncological outcomes. Our aim determine imaging accuracy compared histopathology define the effect inaccurate on patient selection treatment(NT). Staging treatment were determined undergoing resections adenocarcinomas a single tertiary centre(2016-2020). Data obtained 948 patients. The was correct both T N stage 19.68% colon cancer under-staged 18.58%. At resection, 23 (3.36%) had pathological margins; only 7 which been predicted by pre-operative staging. However, 53.85% rectal understaged 26.89%. Thirteen involved(R1)margins; T4 accurately all these cases. There general trend understaging tumor lymphonodal involvement (T p < 0.00001 0.00001) causing failure administrating NT 0.1% with tumor, but not cancer. Preoperative radiological tended understage colonic cancers. In tumours this misled opportunity treat therapy, resulting at