Coronavirus Disease 2019 (COVID-19) in Children - What We Know So Far and What We Do Not

• DOI: 10.1007/s13312-020-1819-5
• Publication Date: 2020-05-21T08:03:42Z
• Authors: S. Balasubramanian; Neha Mohan Rao; Anu Goenka; Marion Roderick; Athimalaipet V Ra...
• Keywords: Coronavirus; Pandemic

Pediatric coronavirus disease-19 (COVID-19) infection is relatively mild when compared to adults, and children are reported have a better prognosis. Mortality in appears rare. Clinical features of COVID-19 include fever cough, but large proportion infected be asymptomatic may contribute transmission. It remains unclear why young adults less severely affected than older individuals, this might involve differences immune system function the elderly and/or expression/function cellular receptor for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)- Angiotensin converting enzyme (ACE2). Laboratory findings chest imaging not specific with COVID-19. Diagnosis by Reverse transcriptase-Polymerase chain reaction (RT-PCR) testing upper or lower respiratory tract secretions. This review additionally considers immunosuppressed children, also suggests management algorithm few who appear present life threatening infection, including potential use antiviral immunomodulatory treatment. The most significant threat global child health from SARS-CoV-2 unlikely related COVID 19 rather socio-economic consequences prolonged pandemic.