Prédiction du devenir neurologique à moyen terme par IRM cérébrale précoce, après encéphalopathie hypoxique-ischémique néonatale traitée par hypothermie contrôlée : apports de la séquence de diffusion et du calcul du coefficient apparent de diffusion (ADC), comparativement aux séquences morphologiques en pondération T1 et T2

• DOI: 10.1007/s13546-015-1081-3
• Publication Date: 2015-06-05T10:09:56Z
• Authors: K. Gaillot; L. Maurin; P. Bertrand; N. Fakhri; E. Saliba; D. Sirinelli
• Keywords: 03 medical and health sciences; 0302 clinical medicine

To compare the value of early Diffusion Weighted Imaging (DWI) (with or without measurement Apparent Coefficient [ADC]) and T1 T2 weighted imaging to predict medium-term neurodevelopmental outcome neonates treated by moderate hypothermia for hypoxic-ischemic encephalopathy (HIE). Prospective followup 27 term after forneonatal HIE; confrontation 9–15 months with neonatal cerebral magnetic resonance (qualitative analysis conventional image DWI cumulative scores quantitative measurements [ADC] 17 brain regions). Infants adverse had higher on DW images. Cumulative were not significantly better than images (area under ROC [Receiver Operating Characteristic] curve: 0.83 versus 0.82 0.89 images). ADC lower infants outcome; caudate lentiform nuclei highest areas curve (0.96 0.99, respectively), but these those After HIE hypothermia, predictive images, alone (without measures ADC) was most regions outcome,