Patient Burden of Nonsegmental Vitiligo: A US Real-World Survey of Dermatologists and Their Patients

• DOI: 10.1007/s13555-024-01165-5
• Publication Date: 2024-05-16T09:05:17Z
• Authors: David Rosmarin; Jennifer H. Lofland; Simran Marwaha; James Piercy; Peter Anderson; Jinan Liu
• Keywords: Vitiligo; Depression; Depigmentation

Vitiligo is a chronic autoimmune disease characterized by destruction of melanocytes, leading to skin depigmentation. can have high quality-of-life burden and profound impact on psychosocial well-being. The objectives this study were describe the self-reported patient among patients with nonsegmental vitiligo ≤ 10% affected body surface area, summarize physician-reported psychological lives, characteristics treatment history, goals, satisfaction. Data drawn from Adelphi Disease Specific Programme™, real-world, cross-sectional survey retrospective data collection physicians vitiligo, collected in United States between October 2021 April 2022. Separate surveys for dermatologists contained questions clinical demographic vitiligo. Treatment satisfaction assessed together quality life. Sixty-one provided 326 area (adults, n = 221; adolescents, 105); 90 those also responded survey. most common treatments topical corticosteroids, calcineurin inhibitors, narrow-band ultraviolet-B phototherapy, main goal being repigmentation. Physician-reported was 56%; 25% reported frustration options. Physicians everyday life 46% patients. Patients 12.7% overall work impairment; mean scores Hospital Anxiety Depression Scale anxiety depression domains 3.5 2.2, respectively, Vitiligo-specific Quality Life index score 26.9. facial involvement experienced higher than without. A their who had including consequences. These findings highlight an unmet need which cells that produce pigment melanin are attacked, causing patches lose color become pale. emotional impacts such as social or distress affect day-to-day well-being individuals. However, there lack studies assess ways affects lives people condition States. Dermatologists answered any currently previously used, how satisfied they results treatment. about own answers questions. Both restoring pale treating both dissatisfied available treatments. impacted aspects Emotional reported, well negative effects patients' due confirm Furthermore, highlights improvements