Impact of dose on lung ventilation change calculated from 4D-CT using deformable image registration in lung cancer patients treated with SBRT

• DOI: 10.1007/s13566-015-0200-0
• Publication Date: 2015-06-12T01:29:02Z
• Authors: Kujtim Latifi; Thomas J. Dilling; Vladimir Feygelman; Eduardo G. Moros; Craig W. Stevens; Jaime L. Montilla...; Geoffrey G. Zhang
• Keywords: Image registration

Objectives Ventilation derived from four-dimensional computerized tomography (4D-CT) using deformable image registration (DIR) has been found to correlate with xenon-enhanced CT ventilation. How radiation dose affects ventilation after stereotactic body radiotherapy (SBRT) is not well understood. In this paper, 4D-CT-derived lung ventilation maps and 3D radiation dose distributions were investigated.