Four new diterpenoids from Isodon eriocalyx var. laxiflora

• DOI: 10.1007/s13659-013-0057-0
• Publication Date: 2013-08-12T18:44:25Z
• Authors: Wei-Guang Wang; Xue Du; Xiao-Nian Li; Bing-Chao Yan; Min Zhou; Hai-Yan Wu; Rui Zhan; Ke Dong; Jian-Xin Pu; Han-Dong Sun
• Keywords: Plant biochemistry; Abietane; Terpene

Four new diterpenoids, laxiflorins S-V (1–4), bearing four different types, and one known compound, laxiflorin O (5), were isolated from Isodon eriocalyx var. laxiflora. Compound 1 was the first example of ent-kauranoids bearing a unique C(24) carbon framework and compound 4 was the first example of 3,4-seco-ent-abietane diterpenoids from the Isodon genus. Their structures were determined by spectroscopic methods (UV, IR, MS, NMR). [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: Supplementary material is available for this article at 10.1007/s13659-013-0057-0 and is accessible for authorized users.