COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study
Male
Case definition; COVID-19; Diagnosis; SARS-CoV-2; Symptoms; Aged; Child; Female; Hospitalization; Hospitals; Humans; Male; Middle Aged; Prospective Studies; SARS-CoV-2; COVID-19
Case definition
[SDV]Life Sciences [q-bio]
150
610
Clinical sciences
COVID-19; Case definition; Diagnosis; SARS-CoV-2; Symptoms
Microbiology
1117 Public Health and Health Services
03 medical and health sciences
0302 clinical medicine
[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system
Diagnosis
wc_505
Humans
ISARIC Clinical Characterisation Group
Prospective Studies
Child
Aged
wa_105
Original Paper
Science & Technology
COVID-19; Case definition; Diagnosis; SARS-CoV-2; Symptoms; Aged; Child; Female; Hospitalization; Hospitals; Humans; Male; Middle Aged; Prospective Studies; SARS-CoV-2; COVID-19
SARS-CoV-2
COVID-19
1103 Clinical Sciences
Middle Aged
Hospitals
3. Good health
Hospitalization
Infectious Diseases
Case definition; COVID-19; Diagnosis; SARS-CoV-2; Symptoms;
Case definition; COVID-19; Diagnosis; SARS-CoV-2; Symptoms
Symptoms
qw_160
Female
wf_100
Life Sciences & Biomedicine
DOI:
10.1007/s15010-021-01599-5
Publication Date:
2021-06-25T15:03:16Z
AUTHORS (1065)
ABSTRACT
Abstract Background The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships age, sex, and nationality to presenting symptoms. Methods International, 60 109 symptomatic laboratory-confirmed COVID-19 recruited from 43 countries between 30 January 3 August 2020. Logistic regression was performed evaluate age sex published case definitions most commonly reported Results ‘Typical’ symptoms fever (69%), cough (68%) shortness breath (66%) were reported. 92% experienced at least one these. Prevalence typical greatest in 30- 60-year-olds (respectively 80, 79, 69%; 95%). They less frequently children (≤ 18 years: 69, 48, 23; 85%), older adults (≥ 70 61, 62, 65; 90%), women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each P < 0.001). common atypical presentations under years nausea vomiting abdominal pain, over confusion. Regression models showed significant differences country. Interpretation This international collaboration has allowed us report reliable symptom data admitted hospital Adults are likely Nausea years. Confusion a frequent presentation Women experience than men.
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