Clinical Features of Bloodstream Infections Associated with Peripheral Versus Central Venous Catheters

• DOI: 10.1007/s40121-019-00257-6
• Publication Date: 2019-07-31T19:02:11Z
• Authors: Keita Tatsuno; Mahoko Ikeda; Yoshitaka Wakabay...; Shintaro Yanagimoto; Shu Okugawa; Kyoji Moriya
• Keywords: Central venous catheter; Bloodstream infection

This study aimed to compare the clinical characteristics and prognoses of central venous catheter-associated bloodstream infections (CVC-BSIs) with peripheral BSIs (PVC-BSIs).This retrospective observational was conducted between April 2011 March 2013 at a teaching hospital in Tokyo, Japan. Adult patients who developed CVC-BSIs PVC-BSIs more than 2 days after admission were included. Patients both excluded. Clinical obtained from medical records, 30-day all-cause mortality measured as outcome.We enrolled 124 PVC-BSI cases 110 CVC-BSI cases. Median age, age-adjusted Charlson score, Sequential Organ Failure Assessment sex, ward type BSI onset did not differ significantly two groups. The median duration catheter indwelling shorter group group. Staphylococcus aureus Gram-negative bacilli frequent coagulase-negative staphylococci (CNS) Candida spp. less prevalence oxacillin resistance among causative S. CNS, mortality, appropriateness empirical definitive antimicrobial therapies groups.The pathogen species distribution varies CVC-BSIs. However, does PVCs are safer CVCs respect BSIs; therefore, it is necessary use similar precautions relevant CVC order avoid unnecessary PVCs.