Burden of Seasonal Influenza A and B in Panama from 2011 to 2017: An Observational Retrospective Database Study

• DOI: 10.1007/s40121-021-00501-y
• Publication Date: 2021-08-23T14:06:06Z
• Authors: Juan Miguel Pascale; Danilo Franco; Raghavendra Devadiga; Rodrigo DeAntonio; Elidia Lourdes Do...; Gael dos Santos; Patricia Juliao
• Keywords: Panama; Seasonal influenza

Influenza A and B viruses constantly evolve cause seasonal epidemics sporadic outbreaks. Therefore, epidemiological surveillance is critical for monitoring their circulation pattern. Trivalent quadrivalent vaccine formulations are available in Panama (until since 2016, respectively). Herein, we analysed influenza patterns Panama. This was a retrospective descriptive analysis of all laboratory-confirmed nasopharyngeal samples recorded between 2011 2017 the nationwide database Gorgas Memorial Institute Health Studies. The involved data relative to demographic information, virus type, subtype lineage, geographic region, treatment outcomes. percentage level mismatch circulating vaccine-recommended lineage assessed each May-October season. Among 1839 cases, 79.6% were type 20.4% B. Most them observed City (54.7%) followed by West (23.2%) Central (16.7%) regions; across regions, cases distributed 4:1 ratio. Overall, approximately half hospitalized (52.0% A; 45.5% B) 11 (0.6%) died. Treatment, usually antimicrobial, administered 15.1% cases. Children less than 2 years old most affected this disease. circulated every year, while only 2012, 2014 2017. In 2012 season, predominant B/Victoria switch B/Yamagata 2014. Both lineages co-circulated 2017, leading 38.9% B-lineage-level mismatch. among ages children inhabitants reported highest rate. co-circulation both led Continuous establish immunization recommendations.