Quantification of the In Vitro Predisposition to Glistening Formation in One Manufacturer’s Acrylic Intraocular Lenses Made in Different Decades

• DOI: 10.1007/s40123-020-00329-8
• Publication Date: 2021-02-05T15:50:23Z
• Authors: Qiang Wang; Timur M. Yildirim; Sonja K. Schickhardt; Grzegorz Łabuz; Ramin Khoramnia; Patrick R. Merz; Hyeck-Soo Son; Donald J. Munro; Elfriede Friedmann; Gerd U. Auffarth
• Keywords: Intraocular lenses; Acrylic resin; Acrylic polymer

Foldable hydrophobic acrylic intraocular lenses (IOLs) are prone to develop a long-term postoperative material change called glistenings. The aim of this study was investigate the changes in predisposition for glistening formation one type IOL from its introduction present day. In laboratory setup, an vitro model used induce glistenings IOLs manufactured by company (Alcon, Fort Worth, TX, USA) different years: 23 1990s-manufacture three-piece (MA30BA/MA60AC) that were explanted 1996 and 1997, five each newer AcrySof models (MA60AC, SA60AT, TFNT00 SN60WF) 2014 2017. Furthermore, Clareon (SY60WF) put through same accelerated aging procedure. number microvacuoles per square millimeter (MV/mm2) determined central part optic compared between groups. mean MV highest Alcon IOLs, with 1289 (± 738) MV/mm2. decreased 650 101), 192 105), 175 112) 47 26) MA60AC, SN60WF, respectively. lowest count obtained group, 1 1) A high induced 1990s. propensity considerably after decade now current use. Even though today's low, essentially glistenings-free.