Performance of Eight Infliximab Population Pharmacokinetic Models in a Cohort of Dutch Children with Inflammatory Bowel Disease

Therapeutic Drug Monitoring Trough Concentration Trough level
DOI: 10.1007/s40262-024-01354-7 Publication Date: 2024-03-15T13:01:41Z
ABSTRACT
Efficacy of infliximab in children with inflammatory bowel disease can be enhanced when serum concentrations are measured and further dosing is adjusted to achieve maintain a target concentration. Use population pharmacokinetic model may help predict an individual's dose requirement. The aim this study was evaluate the predictive performance available models independent cohort Dutch disease.
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