Prevalence and Preventability of Adverse Medicine Events in a Sample of Australian Aged-Care Residents: A Secondary Analysis of Data from the ReMInDAR Trial

• DOI: 10.1007/s40264-023-01299-z
• Publication Date: 2023-04-19T18:02:34Z
• Authors: Lisa M. Kalisch E...; Gerel Dorj; Andre Q. Andrade; Rebecca L. Bilton; Debra Rowett; Joseph Whitehouse; Renly Lim; Nicole L. Pratt; Thu-Lan Kelly; Nibu Parameswaran...; Luke Bereznicki; Imaina Widagdo; Elizabeth E. Roug...
• Keywords: Interquartile range

Aged care residents are vulnerable to the harmful effects of medicines; however, data on prevalence and preventability adverse medicine events in aged scarce. To determine Australian residents. A secondary analysis from Reducing Medicine-Induced Deterioration Adverse Reactions (ReMInDAR) trial was conducted. Potential were identified independently screened by two research pharmacists produce a short-list potential events. An expert clinical panel reviewed each likelihood that event related (based Naranjo Probability Scale criteria). The assessed medicine-related using Schumock-Thornton criteria. There 583 due medicines, involving 154 (62% 248 study participants). median three medication-related (interquartile range [IQR] 1–5) per resident over 12-month follow-up period. most common falls (56%), bleeding (18%) bruising (9%). 482 (83%) preventable, commonly (66% preventable events), (12%) dizziness (8%). Of residents, 133 (54% cohort) had at least one event, with 2 (IQR 1–4) resident. In total, 62% our an 54%