Impedance testing of porous Si3N4 scaffolds for skeletal implant applications

• DOI: 10.1007/s42452-020-2624-4
• Publication Date: 2020-04-06T10:02:46Z
• Authors: Serdar Onat Akbulut; Hamed Ghorbanpoor; Betül Özbek İpteç; Adrian Butterworth; Gamze Avcıoğlu; Leyla Didem Kozacı; Gülsüm Topateş; Damion K. Corrigan; Hüseyin Avcı; Fatma D. Güzel
• Keywords: Biocompatibility; Porous Silicon; Radiodensity

Abstract Si 3 N 4 ceramics show excellent characteristics of mechanical and chemical resistance in combination with good biocompatibility, antibacterial property radiolucency. Therefore, they are intensively studied as structural materials skeletal implant applications. Despite their attractive properties, there limited data the field about vitro studies cellular growth on ceramic materials. In this study, bone cells was investigated porous silicon nitride (Si ) by using electrochemical impedance spectroscopy (EIS). Partial sintering performed at 1700 °C amount additive for production scaffolds. All samples were then sterilized ethylene oxide followed culturing MG-63 osteosarcoma substrates assays. At 20 36 h, EIS results demonstrated that magnitude a result changes culture medium increased after incubation cells. The attributed to uptake charged molecules from medium. appear large changes, especially between 100 1 Hz. Impedance also correlated WST-1 measurements (36 h) DAPI results.