Current progress and limitations of research regarding the therapeutic use of adipose-derived stem cells: literature review

• DOI: 10.1007/s43994-024-00147-9
• Publication Date: 2024-04-17T10:07:13Z
• Authors: Maksym Skrypnyk
• Keywords: Regenerative Medicine

Abstract Background Adipose tissue has recently become one of the most promising and predominant sources mesenchymal stem cells owing to its high accessibility, culturing properties, regenerative potential, relatively fewer ethical considerations. From time adipose-derived (ADSCs) discovery, many beneficial properties have been found, including their regenerative, anti-inflammatory, immunomodulatory, antimicrobial effects. The number publications clinical trials using ADSCs increased significantly worldwide, attesting nature therapeutic ADSCs. Main body abstract In studies, are mainly used treat wounds, multiple sclerosis, soft trauma, aging, diabetes, Parkinson’s disease, bone cartilage regeneration, strokes, spinal cord injuries. Few insignificant adverse effects after ADSC treatment documented, suggesting relative safety for use. Despite significant progress in ADSC-related several issues yet be addressed, a lack standardization ADSC-associated protocols methods obtain them, inconsistent dosages, small numbers patients each group, variable graft purity. This severely complicates our ability compare these making results even similar studies controversial. Short conclusion review described current stage ADSCs-based outcomes limitations, associated with