Evaluation of bacteriostatic and antioxidant activities of various extracts from aerial part of Piper nigrum grown in Gulf countries traditionally used for the treatment of various infectious diseases

• DOI: 10.1007/s43994-024-00149-7
• Publication Date: 2024-04-13T20:10:05Z
• Authors: Doaa Ibrahim Mare...; Salem Said Jaroof...; Mohammad Amzad Ho...
• Keywords: Maceration (sewage)

Abstract Piper nigrum (P. ) is a tropical medicinal plant widely available in Southeast Asian countries including Oman. In It has long history of usage places such as Oman for treating rheumatism, colds, and various infections. Based on the uses, purpose this research to create diverse fractions using increasing solvent polarity from aerial part collected species evaluate their antibacterial antioxidant activities by established bioassays. The was Southern processed standard method. materials were recovered maceration method methanol, methanol raw extracts further fractionated with water extraction, butanol, ethyl acetate (ETA), hexane, dichloromethane are produced different liquid polarities. Each six tested potential at concentrations against DPPH (1, 1-diphenyl-2-picrylhydrazyl) agar diffusion methods. All varied shown promising activity gallic acid. maximum observed hexane extract, while smallest noticed butanol following order: > chloroform extract. efficacy polarities gives moderate two Gram-positive bacteria strains namely S. saprophyticus aureus three Gram-negative P. vulgaris , K. senegalensis E. coli . Among extracts, extract had most activity, whereas activity. remaining four chloroform, acetate, water, all comparable conclusion, greatest chosen types might be employed natural antioxidants treat infectious disorders.