Effect of different treatment strategies on modified Glasgow Prognostic Score (mGPS) in patients with breast cancer

• DOI: 10.1007/s44337-024-00123-6
• Publication Date: 2024-11-14T12:43:44Z
• Authors: Haseena Nawaz; Sadia Fatima; Asif Ali; Awal Mir; Benish Aleem; Sobia Rafiq; Mohammed Alorini

Abstract Background There are various treatment options for breast cancer, but a delayed diagnosis at an advanced stage negatively affects overall survival. Our objective is to investigate the prognostic significance of modified Glasgow Prognostic Score (mGPS) with different modalities. Materials and methods The study was longitudinal cohort conducted in Biochemistry laboratory Institute Basic Medical Sciences Khyber University. Enrolling 121 patients invasive carcinoma from November 2018 February 2021, blood samples were collected stages. Data analysis utilized SPSS ® version 22, employing Kaplan–Meier method survival (OS) calculation. log-rank test assessed P-values OS, chi-square analyzed association treatments. Statistical considered results P-value (p < 0.05). Results indicated that mGPS 2 linked lower survival, while 0 1 associated good Chemo-endocrine therapy exhibited highest median 40.9 months compared other options. Conversely, chemoradiotherapy combined targeted demonstrated lowest 22.5 months. Conclusion findings current research suggested could be used as screening tool cancers receiving therapeutic