Highly efficient approach for characterizing nanometer-sized gold particles by capillary electrophoresis

• DOI: 10.1016/j.aca.2004.08.052
• Publication Date: 2004-12-10T14:33:26Z
• Authors: Fu-Ken Liu; Ying-Ying Lin; Chien-Hou Wu
• Keywords: Nanometre; Nanomaterials; Characterization

Abstract This paper demonstrates that capillary electrophoresis (CE) can be employed for characterizing the sizes of nanometer-scale gold particles. We characterized the gold nanoparticles by effecting CE separation using a buffer of SDS (70 mM) and 3-cyclohexylamino-1-propanesulfonic acid (CAPS; 10 mM) at pH 11.0 and an applied voltage of 18 kV and obtained a linear relationship ( R 2 > 0.99) between electrophoretic mobilities and size for nanoparticles whose diameters fall in the regime from 5.0 ± 0.5 to 41.2 ± 3.3 nm; the relative standard deviations of these electrophoretic mobilities are