Extramammary Paget Disease: A Report of 10 Cases

• DOI: 10.1016/j.adengl.2014.11.009
• Publication Date: 2014-12-06T14:49:59Z
• Authors: G. Blasco-Morente; A. Martín-Castro; C. Garrido-Colmenero; J. Tercedor-Sánchez
• Keywords: Male; Paget Disease, Extramammary; Humans; Female; Neoplasm Invasiveness; Diagnostic Errors; Middle Aged; Aged; 3. Good health

Extramammary Paget disease (EMPD) is a very rare form of intraepithelial adenocarcinoma. We report the cases of EMPD diagnosed in a referral hospital over a 5-year period from 2009 to 2013. Ten cases of EMPD were diagnosed in 4 men and 6 women aged between 50 and 79 years. Erroneous clinical diagnoses led to diagnostic delays of 1 to 5 years in all cases. Six patients had in situ lesions and dermal invasion was observed in the other 4 cases. Four patients had a second neoplasm and 2 of the patients with invasive EMPD died. Because EMPD is rare and its clinical presentation is nonspecific, a high degree of clinical suspicion is required to avoid delays in diagnosis and treatment.