Prognostic value of H2FPEF score in COVID-19

• DOI: 10.1016/j.ahjo.2022.100111
• Publication Date: 2022-03-02T00:51:02Z
• Authors: Priya Patel; Max Ruge; Joanne Michelle D...; Jeanne du Fay de ...; Anupama Rao; Kim A. Williams; Annabelle Santos ...; Maria Rosa R. Cos...; Tisha Suboc; Karolina Marinescu
• Keywords: heart failure with preserved ejection fraction; SARS-CoV-2; COVID-19; Heart Failure with Preserved Ejection Fraction; 03 medical and health sciences; 0302 clinical medicine; RC666-701; 616; Internal Medicine; Medicine and Health Sciences; Diseases of the circulatory (Cardiovascular) system; Influenza Humans; Research Paper

This study sought to assess the predictive value of H2FPEF score in patients with COVID-19.Retrospective study.Rush University Medical Center.A total of 1682 patients had an echocardiogram in the year preceding their COVID-19 admission with a preserved ejection fraction (≥50%). A total of 156 patients met inclusion criteria.Patients were divided into H2FPEF into low (0-2), intermediate (3-5), and high (6-9) score H2FPEF groups and outcomes were compared.Adjusted multivariable logistic regression models evaluated the association between H2FPEF score group and a composite outcome for severe COVID-19 infection consisting of (1) 60-day mortality or illness requiring (2) intensive care unit, (3) intubation, or (4) non-invasive positive pressure ventilation.High H2FPEF scores were at increased risk for severe COVID-19 infection when compared intermediate to H2FPEF score groups (OR 2.18 [CI: 1.01-4.80]; p = 0.049) and low H2FPEF score groups (OR 2.99 [CI: 1.22-7.61]; p < 0.05). There was no difference in outcome between intermediate H2FPEF scores (OR 1.34 [CI: 0.59-3.16]; p = 0.489) and low H2FPEF score.Patients with a high H2FPEF score were at increased risk for severe COVID-19 infection when compared to patients with an intermediate or low H2FPEF score regardless of regardless of coronary artery disease and chronic kidney disease.