Mode of delivery in women with class III obesity: planned cesarean compared with induction of labor

• DOI: 10.1016/j.ajog.2014.06.045
• Publication Date: 2014-06-20T07:49:51Z
• Authors: Akila Subramaniam; Victoria Chapman ...; Amy Reed Goss; Mitchell Dean Alv...; Crystal Reese; Rodney Kirk Edwards
• Keywords: Adult; 2. Zero hunger; Cesarean Section; Postpartum Hemorrhage; Delivery, Obstetric; Obesity, Morbid; Obstetric Labor Complications; 3. Good health; Cohort Studies; Pregnancy Complications; 03 medical and health sciences; Maternal Mortality; Postoperative Complications; 0302 clinical medicine; Pregnancy; Multivariate Analysis; Odds Ratio; Humans; Female; Cesarean Section, Repeat; Labor, Induced; Endometritis; Intraoperative Complications; Retrospective Studies

To compare maternal and neonatal outcomes between planned cesarean delivery and induction of labor in women with class III obesity (body mass index ≥40 kg/m(2)).In this retrospective cohort study, we identified all women with a body mass index ≥40 kg/m(2) who delivered a singleton at our institution from January 2007 to February 2013 via planned cesarean or induction of labor (regardless of eventual delivery route) at 37-41 weeks. Patients in spontaneous labor were excluded. The primary outcome was a composite of maternal morbidity including death as well as operative, infection, and thromboembolic complications. The secondary outcome was a neonatal morbidity composite. Additional outcomes included individual components of the composites. Student t, χ(2), and Fisher exact tests were used for statistical analysis. To calculate adjusted odds ratios, covariates were analyzed via multivariable logistic regression.There are 661 mother-infant pairs that met enrollment criteria-399 inductions and 262 cesareans. Groups were similar in terms of prepregnancy weight, pregnancy weight gain, and delivery body mass index. Of the 399 inductions, 258 had cervical ripening (64.7%) and 163 (40.9%) had a cesarean delivery. After multivariable adjustments, there was no significant difference in the maternal morbidity composite (adjusted odds ratio, 0.98; 95% confidence interval, 0.55-1.77) or in the neonatal morbidity composite (adjusted odds ratio, 0.81; 95% confidence interval, 0.37-1.77) between the induction and cesarean groups.In term pregnant women with class III obesity, planned cesarean does not appear to reduce maternal and neonatal morbidity compared with induction of labor.