Food and Drug Administration warning on anesthesia and brain development: implications for obstetric and fetal surgery

• DOI: 10.1016/j.ajog.2017.08.107
• Publication Date: 2017-09-06T21:33:16Z
• Authors: Olutoyin A. Olutoye; Byron Wycke Baker; Michael A. Belfort; Oluyinka O. Olutoye
• Keywords: Fetal Surgery

(Am J Obstet Gynecol. 2018;218(1):98–102) The United States Food and Drug Administration has warned against the use of general anesthetics and sedation medications for >3 hours in pregnant women in the third trimester and children younger than 3 years old. The anesthetics agents listed included midazolam, propofol, and inhalational anesthetics (isoflurane, sevoflurane, and desflurane). They claim these agents may affect the development of children’s brains.