Pregnancy alters interleukin-1 beta expression and antiviral antibody responses during severe acute respiratory syndrome coronavirus 2 infection

• DOI: 10.1016/j.ajog.2021.03.028
• Publication Date: 2021-03-30T17:27:28Z
• Authors: Morgan L. Sherer; Jun Lei; Patrick S. Creisher; Minyoung Jang; Ramya Reddy; Kristin Voegtline; Sarah Olson; Kirsten Littlefield; Han-Sol Park; Rebecca L. Ursin; Abhinaya Ganesan; Theresa Boyer; Nada Elsayed; Diane M. Brown; Samantha N. Walch; Annukka A.R. Antar; Yukari C. Manabe; Kimberly Jones-Be...; William Christoph...; Andrew J. Satin; Jeanne S. Sheffield; Andrew Pekosz; Sabra L. Klein; Irina Burd
• Keywords: Coronavirus

Severe acute respiratory syndrome coronavirus 2, the disease-causing pathogen of disease 2019 pandemic, has resulted in morbidity and mortality worldwide. Pregnant women are more susceptible to severe at higher risk preterm birth than uninfected pregnant women. Despite this evidence, immunologic effects 2 infection during pregnancy remain understudied.