ZB-06, a vaginal film containing an engineered human contraceptive antibody (HC4-N), demonstrates safety and efficacy in a phase 1 postcoital test and safety study

• DOI: 10.1016/j.ajog.2023.02.024
• Publication Date: 2023-03-02T16:23:29Z
• Authors: Andrea R. Thurman; Thomas R. Moench; Marshall Hoke; Joseph A. Politch; Howard Cabral; Emilie Mausser; Ellena Nador; Josh Morton; Krystal Hamorsky; Kelsi Swope; Barry Bratcher; Deborah J. Anderson; Kevin J. Whaley
• Keywords: Male; Contraceptive Agents; Pregnancy; Semen; Vagina; Humans; Contraceptive Devices, Female; Female; Spermatocidal Agents; 3. Good health

With an unplanned pregnancy rate of 50% or more in many countries, there is urgent need for contraceptives that are accessible and acceptable. To meet the growing demand new contraceptives, ZabBio developed ZB-06, a vaginal film containing HC4-N, human contraceptive antibody inactivates sperm.