OPTN/SRTR 2021 Annual Data Report: Liver

• DOI: 10.1016/j.ajt.2023.02.006
• Publication Date: 2023-02-28T00:03:04Z
• Authors: Allison J. Kwong; Noelle H. Ebel; W. Ray Kim; John R. Lake; Jodi M. Smith; David P. Schladt; Erin M. Schnellinger; Dzhuliyana Handarova; Samantha Weiss; Matthew Cafarella; Jon J. Snyder; Ajay K. Israni; Bertram L. Kasiske
• Keywords: Liver disease

In 2021, liver transplant volume continued to grow, with a record 9,234 transplants performed in the United States, 8,665 (93.8%) from deceased donors and 569 (6.2%) living donors. There were 8,733 (94.6%) adult 501 (5.4%) pediatric recipients. An increase number of donor livers corresponded an overall rate shorter waiting times, although still 10.0% that recovered not transplanted. Alcohol-associated disease was leading indication for both waitlist registration adults, outpacing nonalcoholic steatohepatitis, while biliary atresia remained children. Related allocation policy changes implemented 2019, proportion hepatocellular carcinoma has decreased. Among candidates listed 2020, 37.7% received within 3 months, 43.8% 6 53.3% 1 year. Pretransplant mortality improved children following implementation acuity circle-based distribution. Short-term graft patient survival outcomes up year worsened recipients, which is reversal previous trends coincided onset COVID-19 pandemic early 2020. Longer-term among recipients unaffected, posttransplant rates 13.3% at years, 18.6% 5 35.9% 10 years. distribution prioritization Pediatric had superior compared all time points.