Timing and Causes of Death in Acute Myocardial Infarction Complicated by Cardiogenic Shock (from the RETROSHOCK Cohort)

• DOI: 10.1016/j.amjcard.2022.01.050
• Publication Date: 2022-03-10T05:13:20Z
• Authors: Lise W. Davodian; Jeppe K.P. Larsen; Amalie L. Povlsen; Jakob Josiassen; Ole K.L. Helgestad; Nanna L.J. Udesen; Christian Hassager; Henrik Schmidt; Jesper Kjaergaard; Lene Holmvang; Lisette Okkels Je...; Hanne B. Ravn; Jacob E. Møller
• Keywords: Heart Failure; Male; Myocardial Infarction; Shock, Cardiogenic; Shock; 3. Good health; Out-of-Hospital Cardiac Arrest/complications; Cohort Studies; 03 medical and health sciences; Treatment Outcome; 0302 clinical medicine; Cardiogenic/therapy; Heart Failure/complications; Shock, Cardiogenic/therapy; Cause of Death; Humans; Female; Out-of-Hospital Cardiac Arrest; Aged; Retrospective Studies

Acute myocardial infarction complicated by cardiogenic shock (AMICS) comprises a heterogeneous population with high mortality. Insight in timing and cause of death may improve understanding the condition aid individualization treatment. This was assessed retrospective, multicenter observational cohort study based on 1,716 patients AMICS treated during period 2010 to 2017, whom 904 died before hospital discharge. Patients were identified through national registries review individual charts. In who discharge (median age 72 years [interquartile range (IQR) 63 79], 70% men), 342 (38%) had suffered out-of-hospital cardiac arrest. The most frequent primary (54%), whereas 24% neurologic injury, 20% multiorgan failure (MOF). Time 13 hours (IQR 5 43) for heart failure; 140 95 209) injury; 137 59 321) MOF, p <0.001. causes presenting arrest (OHCA) were: injury 57%, as opposed 4% not OHCA, conclusion, AMICS, mainly followed MOF. Median time from first medical contact only dying causes. risk low without OHCA.