Rational design and crystallographic analysis of novel isoform-selective TRKA inhibitors for cancer therapy

• DOI: 10.1016/j.apsb.2022.10.012
• Publication Date: 2022-10-19T08:41:16Z
• Authors: Guan Wang; Yongya Wu; Chengyong Wu; Wen Shuai; Tingting Jiang; Aoxue Wang; Faqian Bu; Qiu Sun; Liang Ouyang
• Keywords: 0301 basic medicine; 03 medical and health sciences; Cancer therapy; Drug discovery; TRKA; Therapeutics. Pharmacology; RM1-950; Letter to the Editor; Co-crystal structure; Selective inhibitor