Multiple Ground-Glass Opacity in Metastasis of Malignant Melanoma Diagnosed By Lung Biopsy

• DOI: 10.1016/j.athoracsur.2004.03.096
• Publication Date: 2004-12-28T23:44:54Z
• Authors: Riki Okita; Motohiro Yamashita; Masao Nakata; Norihiro Teramoto; Akihiro Bessho; Hiroshi Mogami
• Keywords: Lung Neoplasms; Biopsy; Nose Neoplasms; Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Middle Aged; 3. Good health; Dacarbazine; Diagnosis, Differential; Picibanil; 03 medical and health sciences; 0302 clinical medicine; Chemotherapy, Adjuvant; Antineoplastic Combined Chemotherapy Protocols; Humans; Melanocytes; Female; Nasal Cavity; Tomography, X-Ray Computed; Uracil; Antineoplastic Agents, Alkylating; Melanoma; Tegafur

Focal ground-glass opacity (GGO) on computed tomography has been reported in several disorders including inflammatory disease and primary neoplastic lesion of the lung. We report a case of malignant melanoma of the nasal cavity metastatic to the lungs in which multiple pulmonary nodules showed GGO. Lung biopsy specimen demonstrated melanoma cells proliferating in a lepidic fashion along the thickened alveolar wall simulating bronchioloalveolar carcinoma. Metastatic lung tumor showing GGO is uncommon.