Clinical Application of Intermittent Pressure-Augmented Retrograde Cerebral Perfusion

• DOI: 10.1016/j.athoracsur.2010.03.024
• Publication Date: 2010-09-23T08:24:50Z
• Authors: Hiroshi Kubota; Shinichi Takamoto; Hideaki Yoshino; Kazuhiko Kitahori; Mitsuhiro Kawata; Kunihiko Tonari; Hidehito Endo; Hiroshi Tsuchiya; Yusuke Inaba; Yu Takahashi; Kenichi Sudo
• Keywords: Adult; Spectroscopy, Near-Infrared; Cardiovascular Surgical Procedures; Brain; Aorta, Thoracic; Takayasu Arteritis; Brain Ischemia; Perfusion; 03 medical and health sciences; 0302 clinical medicine; Humans; Female; Oximetry

Brain protection is important during aortic arch surgery, especially in patients with cerebral ischemia. We clinically applied the effectiveness of a novel protocol of retrograde cerebral perfusion with intermittent pressure augmentation for brain protection in a canine model, as described in a previous report. Although, in our patient the brachiocephalic artery and left subclavian artery were occluded as a result of aortitis, there was a history of right cerebral infarction, recovery of consciousness, and no neurologic sequelae. Near-infrared oximetry showed recovery of intracranial blood oxygen saturation every time the pressure was augmented.