PDE4 inhibition alleviates HMGB1/C1q/C3-mediated excessive phagocytic pruning of synapses by microglia and depressive-like behaviors in mice

• DOI: 10.1016/j.bbi.2025.02.007
• Publication Date: 2025-02-11T22:02:46Z
• Authors: Qian Zhao; Chunyuan Zeng; Fulan Luo; Zihong Xian; Huizhen Wen; Xingxing Tu; Rifang Yang; Yijun Sun; Xiangling Zheng; Jiangping Xu; Haitao Wang
• Keywords: Synaptic Pruning; HMGB1; Pruning