Gut microbiota regulate stress resistance by influencing microglia-neuron interactions in the hippocampus

• DOI: 10.1016/j.bbih.2024.100729
• Publication Date: 2024-01-23T18:14:02Z
• Authors: Haili He; Hui He; Li Mo; Qingsong Yuan; Chenghong Xiao; Qiman Ma; Saini Yi; Tao Zhou; Zili You; Jinqiang Zhang
• Keywords: 0301 basic medicine; 0303 health sciences; Depression; Full Length Article; Stress resilience; Microglia-neuron interaction; Neurosciences. Biological psychiatry. Neuropsychiatry; Gut microbiota; Immune checkpoint; Synaptic plasticity; RC321-571

Communication among the brain, gut and microbiota in is known to affect susceptibility stress, but mechanisms involved are unclear. Here we demonstrated that stress resistance mice was associated with more abundant