Soluble T-cadherin secretion from endothelial cells is regulated via insulin/PI3K/Akt signalling

• DOI: 10.1016/j.bbrc.2024.150403
• Publication Date: 2024-07-14T10:44:26Z
• Authors: Tomonori Okita; Shunbun Kita; Shiro Fukuda; Yuta Kondo; Taka-aki Sakaue; Masahito Iioka; Keita Fukuoka; Keitaro Kawada; Hirofumi Nagao; Yoshinari Obata; Yuya Fujishima; Takeshi Ebihara; Hisatake Matsumoto; Satoshi Nakagawa; Tadashi Kimura; Hitoshi Nishizawa; Iichiro Shimomura
• Keywords: Signalling; VE-cadherin

Our recent report showed that soluble T-cadherin promotes pancreatic beta-cell proliferation. However, how and where the secretion of is regulated remain unclear.